历任荷兰皇家科学院胡布勒⽀研究所所长，荷兰皇家科学院院长，乌德勒支玛西玛公主小儿肿瘤中首席席科学家/研究主任。并兼任国际分化学会（ISD）主席，美国癌症研究协会理事，国际干细胞研究学会（ISSCR）主席，罗氏控股有限公司非执行董事等重要职务，2020年起加盟丹望医疗科技（杭州）有限公司任首席战略官。 

国际类器官研究鼻祖，首次发现肠道干细胞标志物Lgr5，建立体外3D类器官培养体系，开创了类器官作为疾病研究模型的时代。发表SCI论⽂600多篇，引用次数95000次，h指数为253（Scopus）。Hans是Cell，EMBO，Gastroenterology， Cell Stem Cell等多个国际顶级杂志的编辑委员会成员。 

荣获多个生物医学领域国际奖项，2004年获得影响力仅次于诺贝尔奖的瑞士日内瓦Louis-Jeantet 医学奖，2013年获得被誉为“科学界奥斯卡”的生命科学突破奖。并在Louis-Jeantet奖，加拿大盖尔德纳奖，生命科学突破奖，AACR国际癌症研究奖，美国国家科学院科瓦连科奖章等重要国际奖项中担任评审。

研究方向

Wnt 信号调控基因表达。首次发现 Lgr5 作为成体干细胞标记物，并且这些 干细胞可以培养成类器官，并且无限扩增。在体外培养健康或者疾病组织的微 型器官，用于基础研究、疾病诊断和再生医学。

获得奖项

2018    西班牙巴塞罗那欧洲科学院伊拉斯莫斯奖章

2017    德国之星与优异奖、东京高松公主优绩奖

2016    德国汉堡 Ilse&Helmut Wachter 奖、阿姆斯特丹 Swammerdam medaille

奖、德国柯尔柏欧洲科学奖、Kazemi 生物医学研究卓越奖、荷兰皇家科 学院院士奖

2015    ISSCR-McEwen 创新奖

2014   荷兰国家图标、Struyvenberg 欧洲临床研究学会（ESCI）奖、AACR 学院院士、马萨诸塞州综合医院癌症研究奖

2013    生命科学突破奖

2012    奈德兰狮子骑士勋章、Heineken 医学奖、美国胃肠病学会威廉.博蒙特

奖、巴黎癌症研究协会 LeopoldGriffuel 奖

2011    阿姆斯特丹科尔夫奖

2010    欧洲胃肠病联合会研究奖

2009    阿姆斯特丹威廉米娜女王荷兰癌症协会奖

2008    德国梅因堡癌症研究奖、约瑟芬.奈夫肯斯癌症研究奖

2005   纽约 Katheariine Berkan Judd 奖、法国“荣誉骑士勋章”、阿姆斯特丹科

学与社会奖

2004    瑞士日内瓦 Louis-Jeantet 医学奖

2001    荷兰研究理事会（NWO）斯宾诺莎奖、欧洲临床研究学会奖

2000    Catharijne 医学研究奖

担任奖项评审

2017   科瓦连科奖章（美国国家科学院）、邵逸夫奖（香港）、法兰基奎奖

（布鲁塞尔）

2015   保罗.詹森博士奖、AACR  国际癌症研究奖

2014   生命科学突破奖（旧金山）

2013-2015   加拿大盖尔德纳奖（多伦多） 2008-2015   Louis Jeantet 奖（日内瓦）

荣誉称号

2019    苏格兰国家科学与文学院爱丁堡皇家学会荣誉院士、伦敦皇家自然科学

学会外籍会员、纽约科学院院士

2017    德国 Orden 蓝马克斯勋章科学和艺术成员

2016    法国科学研究院院士

2014    美国国家科学院院士

2012    荷兰皇家科学与人文学会成员、美国艺术与科学研究院院士

2009    欧洲科学院院士

2000    荷兰皇家科学院（KNAW）院士

1999    欧洲分子生物学组织（EMBO）成员

名誉教授

上海复旦大学复旦类器官中心客座主任、澳大利亚墨尔本大学客座教授、以色 列雷霍沃特维兹曼研究所客座教授、香港大学杰出客座教授、TEFAF 肿瘤科主 任、中南大学客座教授

担任编辑委员会成员杂志

EMBO 、Gastroenterology 、Cell 、Genes & Develepment 、Stem Cell Reports、 Cell Stem Cell 、Annual Review of Cancer Biology

咨询顾问

巴塞尔罗氏控股有限公司非执行董事、阿姆斯特丹生命科学合作伙伴科学顾 问、乌德勒支 Merus 科学顾问委员会、国际干细胞研究学会（ISSCR）主席、纽 约卡里奥普科学咨询委员会、旧金山 Surrozen 科学顾问委员会、波士顿分贝治疗 学科学顾问委员会、伦敦弗朗西斯.克里克研究所科学顾问委员会、维也纳分子病 理研究所科学顾问委员会、美国癌症研究协会理事、阿姆斯特丹国家科学咨询委 员会 NKI-AVL、国际分化学会（ISD）主席、瑞士实验癌症研究所科学顾问委员 会。

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